Nanosponge - A Novel Drug Delivery System

Nanosponge and Micro Sponges: a Novel Drug Delivery System

Nanosponge and Microsponge delivery System was originally developed for topical delivery of drugs can also be used for controlled oral delivery of drugs using water soluble and bioerodible polymers. It holds a promising future in various pharmaceutical applications in the coming years like enhanced product performance and elegancy, extended release, reduced irritation, improved thermal, physica...

Nanosponge: New Colloidal Drug Delivery System for Topical Delivery

Topical drug delivery system faced many problems like poor permeability, skin irritation, allergic reactions etc. The new developed colloidal system called nanosponge has potential to overcome these problems. Nanosponge are tiny sponges having size of about a virus and can easily penetrate through skin. Nanosponge play vital role in targeting drug delivery in a controlled manner. Both lipophili...

Nanosponge-Mediated Drug Delivery Lowers Intraocular Pressure.

PURPOSE We examined the efficacy of an extended-release drug delivery system, nanosponge (NS) encapsulated compounds, administered intravitreally to lower intraocular pressure (IOP) in mice. METHODS Bilateral ocular hypertension was induced in mice by injecting microbeads into the anterior chamber. Hypertensive mice received NS loaded with ocular hypotensive drugs via intravitreal injection a...

Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...

Microemulsions: A potential novel drug delivery system